Router 1
Router 1 picks up the packet and strips the Network Interface layer information off the packet. The router determines that the packet is destined for IP address 192.168.4.22.
Given the subnet mask, the router determines that the network identifier is 192.168.4.0.
Router 1 then consults its routing table to determine to which router port the packet should be sent.
When Router 1 consults its routing table, it sees that packets destined for network 192.168.4.0 must be sent to Router 2. The Router 1 interface leading to Router 2 is 192.168.2.1.
Router 1 then repackages the Network Interface part of the data frame and transmits the packet out interface 192.168.2.1. The destination IP address remains unchanged.